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Na-Dependent Glucose Transporter

Catalog# Product Description Host Species Nature Cross reactivity Quantity Volume Price
SGLT-101AP SGLT mid-region antibodies Rabbit AP r, m, h 100.0 ug 150-500 ul $245.00
SGLT-112AP SGLT C-terminal antibodies Rabbit AP r, m, h 100.0 ug 150-500 ul $245.00
FITC-SGLT100 FITC-conjugated mid-region antibodies Rabbit FITC-AP r, m, h 100.0 ug 150-500 ul $350.00
FITC-SGLT110 FITC-conjugated C-terminal antibodies Rabbit FITC-AP r, m, h 100.0 ug 150-500 ul $350.00
P-SGLT100 Mid-region antigenic blocking peptide n/a Synthetic peptide n/a 250.0 ug 100 ul $125.00
P-SGLT110 C-terminal antigenic blocking peptide n/a Synthetic peptide n/a 250.0 ug 100 ul $125.00
PC-SGLT WB positive control for SGLT n/a Protein n/a 0.0 ug 150 ul $185.00
Thirteen types of glucose transport carrier proteins designated as Glut 1-13 facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue-specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers. 
 The Na-Dependent Glucose transporter (Sglt1)-selective antibodies were generated against unique C-terminal peptides characteristics of a particular Glut family. FabGennix Inc. has   generated highly specific rabbit anti-sodium dependent glucose transporter (SGLT1) polyclonal antibodies utilizing mostly C-terminal peptide sequences. These antibodies have been fully characterized for cross reactivity with in the Glut family and with other cellular proteins. FabGennix Inc. has produced antibodies to multiple epitopes on the same protein that will facilitate studies utilizing interspecies cross reactivity.
FabGennix Inc. provides SGLT Western blot positive control in “ready-to-use” SDS-PAGE sample buffer. The SGLT positive control appears as a diffuse band of 69-72 kDa and co-migrates with rat jejunal sodium-dependent glucose transporter protein on a 10% SDS-PAGE. 

For research use only, not for diagnostic or therapeutic use.

Data Sheets
Sodium-Dependent Glucose Transporter

MSDS

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